gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD19 on B cells and recruits FcγR-bearing effector cells to induce ADCC and ADCP, leading to apoptosis and depletion of CD19+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell antigen; Fab-mediated binding
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05626322
disease_id_num_tar_ref
1609
drug_id_num_tar_ref
4360