gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 antibody binds CD20 on B cells, triggering direct caspase-independent cell death and recruiting effector cells via FcγRIIIa to mediate ADCC (with minimal CDC).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type II anti-CD20 binding; binds extracellular domain
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05653271
disease_id_num_tar_ref
1625
drug_id_num_tar_ref
4396