gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize GD2 via the CAR, become activated, and kill GD2-expressing cells through perforin/granzyme-mediated cytolysis (and Fas/FasL apoptosis), with supportive cytokine release.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
dual-target CAR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06836505
disease_id_num_tar_ref
1638
drug_id_num_tar_ref
4429