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gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The target is unspecified (UNKNOWN), and there is no evidence SHR-A1811 binds it. SHR-A1811 is an ADC that kills only antigen-positive cells via binding, internalization, linker cleavage, and intracellular release of a cytotoxic payload (e.g., a topoisomerase I inhibitor), causing DNA damage and apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Target antigen and payload not specified in the trial record for SHR-A1811
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06433609
disease_id_num_tar_ref
1656
drug_id_num_tar_ref
4480