gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Belantamab mafodotin binds BCMA, is internalized, and releases the MMAF payload to disrupt microtubules and kill the cell; its afucosylated IgG also engages Fc receptors to mediate ADCC/ADCP.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05714839
disease_id_num_tar_ref
1658
drug_id_num_tar_ref
4484