gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 IgG1 binds CD20 on B cells and induces killing via Fc-mediated ADCC by effector cells, complement-dependent cytotoxicity (CDC), and apoptosis upon crosslinking.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; primary target
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT04680962
disease_id_num_tar_ref
1672
drug_id_num_tar_ref
4517