gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine primes neoantigen-specific CD8+ T cells via APC HLA I/II presentation; activated CTLs recognize neoantigen–HLA on tumor cells and kill them via perforin/granzyme-mediated apoptosis (and Fas–FasL).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Somatic mutation–derived peptides presented by patient HLA class I/II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05749627
disease_id_num_tar_ref
1692
drug_id_num_tar_ref
4583