gene_symbol
DLL3
hgnc_id
HGNC:2909
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific T-cell engager binds DLL3 on target cells and CD3 on T cells, forming an immune synapse that activates TCR/CD3 signaling and triggers perforin/granzyme-mediated killing of DLL3-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface Notch pathway protein overexpressed in SCLC
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06502977
disease_id_num_tar_ref
189
drug_id_num_tar_ref
515