gene_symbol
HLA-DPB1
hgnc_id
HGNC:4940
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The vaccine primes neoantigen-specific T cells that kill tumor cells presenting those neoantigens; HLA-DPB1 on APCs is only for peptide presentation and is not a cytotoxic target.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Determines DP peptide-binding specificity
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05749627
disease_id_num_tar_ref
1692
drug_id_num_tar_ref
4583