gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Blinatumomab bridges CD3 on T cells to CD19 on target cells, forming an immune synapse and activating T-cell cytotoxicity that kills CD19+ cells via perforin/granzyme-mediated apoptosis (MHC-independent).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06257394
disease_id_num_tar_ref
1696
drug_id_num_tar_ref
4592