gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds GD2 on target cells and triggers Fc-mediated ADCC (e.g., NK cells/macrophages) and complement-dependent cytotoxicity, causing lysis of GD2-positive cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface glycolipid (ganglioside); tumor-associated antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05400603
disease_id_num_tar_ref
1700
drug_id_num_tar_ref
4606