gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CD19 via the CAR and directly kill CD19+ cells through T‑cell activation with perforin/granzyme-mediated apoptosis (and death-receptor signaling).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HLA-independent CAR binding to cell-surface CD19 on B-lineage cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06585514
disease_id_num_tar_ref
1762
drug_id_num_tar_ref
4731