gene_symbol
LILRB4
hgnc_id
HGNC:6608
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
STAR-engineered T cells bind LILRB4 on target cells, signal via the native TCR/CD3 complex, and kill LILRB4+ cells through perforin/granzyme-mediated cytolysis (and related CTL effector mechanisms).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Dual-epitope recognition on LILRB4
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05739409
disease_id_num_tar_ref
1801
drug_id_num_tar_ref
4827