gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
other
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CD20+ cells are killed when coated with anti-CD20 antibodies; the infused allogeneic NK cells bind antibody Fc via CD16 and mediate ADCC (perforin/granzyme-mediated lysis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Target is opsonized by anti-CD20 IgG; NK engages antibody Fc via CD16 (ADCC)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06265220
disease_id_num_tar_ref
199
drug_id_num_tar_ref
539