gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 IgG1 binds CD20 on B cells and triggers their depletion via Fc-mediated ADCC (NK cells/macrophages), with some complement-dependent cytotoxicity and apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen on pre-B to mature B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06668324
disease_id_num_tar_ref
1819
drug_id_num_tar_ref
4870