gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Imvotamab binds CD3 on T cells to engage and activate them; the activated T cells and complement kill CD20+ B cells. CD3+ T cells are not directly targeted for killing.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD3 epsilon chain within the TCR-CD3 complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06041568
disease_id_num_tar_ref
1820
drug_id_num_tar_ref
4871