gene_symbol
DLL3
hgnc_id
HGNC:2909
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
DLL3xCD3 T-cell–engaging antibody bridges DLL3 on target cells to CD3 on T cells, forming an immune synapse that activates T cells to release perforin/granzymes and kill DLL3-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor cell-surface antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06077500
disease_id_num_tar_ref
1826
drug_id_num_tar_ref
4883