gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine delivers HPV18 E6/E7 to APCs, inducing E6-specific CD8+ T cells that recognize E6 peptides on MHC I of tumor cells and kill them via perforin/granzyme cytotoxicity.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HPV type 18 oncoprotein
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05799144
disease_id_num_tar_ref
1857
drug_id_num_tar_ref
4949