gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccinia-vectored vaccine drives APC presentation of HPV18 E7 peptides, inducing HPV-specific CD8+ T cells that recognize E7 on MHC I of tumor cells and kill them via perforin/granzyme (and Fas/FasL) pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HPV type 18 oncoprotein
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05799144
disease_id_num_tar_ref
1857
drug_id_num_tar_ref
4949