gene_symbol
CD38
hgnc_id
HGNC:1667
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD38 IgG1 binds CD38 and triggers complement-dependent cytotoxicity, Fc-mediated ADCC by NK cells, antibody-dependent phagocytosis, and can induce apoptosis of CD38+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type II cell-surface glycoprotein; ectoenzyme (NADase/cyclase)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06889948
disease_id_num_tar_ref
1859
drug_id_num_tar_ref
4953