gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds GD2 on tumor cells and recruits immune effectors via Fc (NK cells/macrophages) to mediate ADCC and antibody-dependent phagocytosis; also activates complement for CDC, leading to target-cell lysis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Ganglioside glycolipid abundantly expressed on neuroblastoma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06275334
disease_id_num_tar_ref
1870
drug_id_num_tar_ref
4976