gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells expressing a CD19-directed KIR-based receptor bind CD19 and are activated to kill CD19+ cells via perforin/granzyme-mediated cytolysis (and Fas/FasL), with cytokine release.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface B-cell antigen on malignant and normal B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06544265
disease_id_num_tar_ref
207
drug_id_num_tar_ref
565