gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The antibody binds Env on infected cells and engages FcγR-bearing effectors to trigger ADCC (NK cells) and ADCP (macrophages; ± complement), killing Env-expressing cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Conserved CD4-binding site epitope on Env; mediates viral entry neutralization
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05729568
disease_id_num_tar_ref
1922
drug_id_num_tar_ref
5152