gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Blinatumomab bridges CD3+ T cells to CD19+ cells, forming an immunologic synapse that triggers T‑cell perforin/granzyme release and cytokine-mediated killing (MHC-independent).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell lineage marker on leukemia/lymphoma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06220487
disease_id_num_tar_ref
1929
drug_id_num_tar_ref
5171