gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Epcoritamab binds CD3ε on T cells to activate and redirect them to kill CD20-positive B cells; CD3ε-expressing T cells are not the targets of cytotoxicity.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Targets the CD3ε chain within the TCR/CD3 complex on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06112847
disease_id_num_tar_ref
1934
drug_id_num_tar_ref
5181