gene_symbol
LILRB4
hgnc_id
HGNC:6608
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Engineered STAR-T cells bind LILRB4 via synthetic receptors and signal through native TCR/CD3 to trigger T-cell cytotoxicity (perforin/granzyme and death-receptor pathways) killing LILRB4+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
also known as ILT3
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05913804
disease_id_num_tar_ref
1935
drug_id_num_tar_ref
5183