gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CD19 on target B cells, become activated, and kill via perforin/granzyme release and death receptor pathways (e.g., Fas-FasL).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen targeted by CAR
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06323525
disease_id_num_tar_ref
1939
drug_id_num_tar_ref
5190