gene_symbol
SLAMF7
hgnc_id
HGNC:21394
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Elotuzumab binds SLAMF7 on myeloma cells and its Fc engages Fcγ receptors on NK cells to trigger antibody‑dependent cellular cytotoxicity (ADCC); it also activates NK cells via SLAMF7, enhancing killing.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface glycoprotein highly expressed on multiple myeloma cells and on NK cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06163040
disease_id_num_tar_ref
1949
drug_id_num_tar_ref
5219