gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD20 on B cells and induces complement-dependent cytotoxicity (MAC lysis), antibody-dependent cellular cytotoxicity via FcγR-bearing effector cells (e.g., NK cells/macrophages), and apoptosis upon CD20 cross-linking.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B cell surface antigen on pre-B and mature B lymphocytes
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05682196
disease_id_num_tar_ref
1955
drug_id_num_tar_ref
5235