gene_symbol
HLA-A
hgnc_id
HGNC:4931
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TIL recognize tumor antigen peptide–HLA-A complexes via their native TCRs and directly kill target cells through perforin/granzyme release and Fas–FasL signaling.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–MHC complex on urothelial carcinoma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05768347
disease_id_num_tar_ref
1965
drug_id_num_tar_ref
5252