gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 IgG1 binds CD20 on B cells and induces Fc-mediated effector killing (ADCC/ADCP) and complement-dependent cytotoxicity, leading to lysis/apoptosis of CD20+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface antigen on pre-B and mature B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06780150
disease_id_num_tar_ref
11
drug_id_num_tar_ref
23