gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Obinutuzumab binds CD20 on B cells, engaging FcγRIIIa on NK cells/macrophages to drive ADCC/ADCP and also triggers direct, caspase‑independent apoptosis (with relatively low CDC).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type II anti-CD20
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06634589
disease_id_num_tar_ref
214
drug_id_num_tar_ref
587