gene_symbol
CTAG1B
hgnc_id
HGNC:2491
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Adoptively transferred TAA-specific CTLs recognize NY-ESO-1 peptide presented on HLA class I via their TCR and induce apoptosis of target cells through perforin/granzyme release (and Fas/FasL).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
HLA class I–restricted TCR recognition of peptide epitope; also known as CTAG1A/CTAG1B (NY-ESO-1)
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05134740
disease_id_num_tar_ref
1972
drug_id_num_tar_ref
5275