gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Adoptively transferred TCR-native CTLs recognize SSX-derived peptides on HLA class I and directly kill target cells via perforin/granzyme-mediated cytolysis (with cytokine-mediated effects).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Family target (e.g., SSX2); HLA class I–restricted TCR recognition of peptide epitope
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05134740
disease_id_num_tar_ref
1972
drug_id_num_tar_ref
5275