gene_symbol
KIT
hgnc_id
HGNC:6342
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Blocks SCF–KIT signaling, withdrawing survival/proliferation signals and leading to apoptosis/depletion of KIT-expressing cells (e.g., HSCs, mast cells); no cytotoxic payload or T‑cell engagement.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Stem cell factor (SCF) receptor; receptor tyrosine kinase
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06162728
disease_id_num_tar_ref
1998
drug_id_num_tar_ref
5346