gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR engagement on engineered T cells triggers activation and direct killing of antigen-expressing cells via perforin/granzyme-mediated cytolysis (and related apoptotic pathways).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Target antigen for the CAR T cells is not specified in the clinical trial record.
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06058858
disease_id_num_tar_ref
2000
drug_id_num_tar_ref
5349