gene_symbol
CD79B
hgnc_id
HGNC:1699
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD79b-specific CAR T cells recognize CD79b on B cells and directly kill them via T‑cell activation and perforin/granzyme-mediated cytolysis (MHC‑independent).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Recognizes the extracellular domain of CD79b (Ig-beta/B29) on B cells in an MHC-independent manner
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06849921
disease_id_num_tar_ref
215
drug_id_num_tar_ref
591