gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Autologous TILs recognize tumor-associated peptide–HLA class I complexes via their TCRs and directly kill target cells by perforin/granzyme release and Fas–FasL–mediated apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Recognized by CD8+ TILs via endogenous TCR; shared TAAs presented on HLA-A/B/C
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05676749
disease_id_num_tar_ref
2052
drug_id_num_tar_ref
5491