gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TILs recognize the tumor-associated peptide–HLA class I complex via their TCR and directly kill the presenting cell through perforin/granzyme-mediated cytotoxicity (and Fas–FasL apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Examples may include differentiation or cancer-testis antigens; recognized by CD8+ TILs as peptide–HLA class I complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06481592
disease_id_num_tar_ref
2059
drug_id_num_tar_ref
5506