gene_symbol
CD276
hgnc_id
HGNC:19137
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
B7-H3–specific CAR T cells recognize B7-H3 on target cells and directly kill them via T-cell cytotoxic mechanisms (perforin/granzyme release and death receptor pathways such as Fas/FasL).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
tumor-associated cell-surface antigen on pediatric CNS tumors
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05835687
disease_id_num_tar_ref
2063
drug_id_num_tar_ref
5515