gene_symbol
CD2
hgnc_id
HGNC:1639
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD2-specific CAR T cells bind CD2 on target cells, activate, and kill via perforin/granzyme-mediated cytolysis (apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell surface antigen; MHC-independent CAR recognition
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06849921
disease_id_num_tar_ref
215
drug_id_num_tar_ref
597