gene_symbol
GPRC5D
hgnc_id
HGNC:13310
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize GPRC5D on target cells and, upon engagement, kill them via T‑cell cytotoxic mechanisms, primarily perforin/granzyme-mediated lysis (with possible Fas–FasL signaling).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface GPCR antigen overexpressed on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06297226
disease_id_num_tar_ref
2076
drug_id_num_tar_ref
5549