gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize CD19 on target cells, become activated, and kill them via T‑cell cytotoxic pathways (perforin/granzyme-mediated lysis and Fas–FasL apoptosis) after antigen engagement.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
scFv-based CAR binding domain
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06346912
disease_id_num_tar_ref
2112
drug_id_num_tar_ref
5655