gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BAFF-ligand-based CAR on the engineered T cells binds BCMA, triggering T-cell activation and perforin/granzyme-mediated killing of the target cell.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
BAFF ligand-based CAR binding domain
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06346912
disease_id_num_tar_ref
2112
drug_id_num_tar_ref
5655