gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-NK cells bind CD19 via the CAR, triggering NK activation and degranulation to kill CD19+ cells through perforin/granzyme-mediated cytolysis (and death receptor pathways).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface B-cell antigen; HLA-independent CAR binding
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06596057
disease_id_num_tar_ref
2160
drug_id_num_tar_ref
5769