gene_symbol
TNFRSF8
hgnc_id
HGNC:11923
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD30-specific CAR-T cells bind CD30 on target cells, triggering MHC-independent T-cell activation and perforin/granzyme-mediated cytolysis (and Fas/FasL apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06494371
disease_id_num_tar_ref
2187
drug_id_num_tar_ref
5841