gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-directed CAR T cells bind CD19 on target cells, become activated via CD3ζ/costimulatory signaling, and kill through immune-synapse–mediated perforin/granzyme cytolysis (and related death receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell surface B-cell antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06718244
disease_id_num_tar_ref
2201
drug_id_num_tar_ref
5892