gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
GD2-targeted CAR T cells recognize GD2 on tumor cells, activate, form an immune synapse, and induce cytolysis via perforin/granzyme (with possible Fas/FasL and cytokine-mediated apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface ganglioside (glycolipid) antigen on tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05298995
disease_id_num_tar_ref
2206
drug_id_num_tar_ref
5901