gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Autologous TILs recognize the tumor-associated peptide–HLA class I via native TCRs and directly kill the presenting cells through perforin/granzyme release (and Fas–FasL), with IFN-γ/TNF contributing to apoptosis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–MHC class I complex (HLA-A/B/C); recognized by CD8+ T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06613152
disease_id_num_tar_ref
2223
drug_id_num_tar_ref
5956