gene_symbol
CLEC12A
hgnc_id
HGNC:31713
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CLL-1 CAR T cells recognize CLL-1 on target cells, activate, and kill them via T cell cytotoxic mechanisms (perforin/granzyme and death-receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CAR recognizes cell-surface CLEC12A on AML blasts/LSCs
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06128044
disease_id_num_tar_ref
2277
drug_id_num_tar_ref
6096